Early life, current socioeconomic position and serum lipids in young adulthood of participants in a cohort study initiated in 1978/1979
| Autor: | Vânia Maria Farias de Aragão, F. Lamy Filho, H. Bettiol, Rubenice Amaral da Silva, Marco Antonio Barbieri, Antônio Augusto Moura da Silva, Rosângela Fernandes Lucena Batista, F.P. Figueiredo |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male medicine.medical_specialty Socioeconomic position Physiology Immunology Biophysics Blood lipids Ocean Engineering Biochemistry chemistry.chemical_compound Internal medicine medicine Humans General Pharmacology Toxicology and Pharmaceutics Young adult Child Socioeconomic status Triglycerides Ldl cholesterol Triglyceride Cholesterol business.industry General Neuroscience Cell Biology General Medicine Endocrinology Social Class chemistry Cardiovascular Diseases Female lipids (amino acids peptides and proteins) Epidemiologic Methods business Brazil Demography Cohort study |
| Zdroj: | Brazilian Journal of Medical and Biological Research. 40:1267-1276 |
| ISSN: | 1414-431X 0100-879X |
| DOI: | 10.1590/s0100-879x2006005000149 |
| Popis: | The association between socioeconomic position (SEP) and serum lipids has been little studied and the results have been controversial. A total of 2063 young adults born in 1978/79 were evaluated at 23-25 years of age in the fourth follow-up of a cohort study carried out in Ribeirao Preto, SP, Brazil, corresponding to 31.8% of the original sample. Total serum cholesterol (TC), triglycerides, high-density cholesterol (HDL cholesterol) and low-density cholesterol (LDL cholesterol) were analyzed according to SEP at birth and during young adulthood. SEP was classified into tertiles of family income and a cumulative score of socioeconomic disadvantage was created. TC was 11.85 mg/100 mL lower among men of lower SEP in childhood (P < 0.01) but no difference was found in women, whereas it was 8.46 lower among men (P < 0.01) and 8.21 lower among women of lower SEP in adulthood (P < 0.05). Individuals of lower SEP had lower LDL and HDL cholesterol, with small differences between sexes and between the two times in life. There was no association between SEP and triglyceride levels. After adjustment of income at one time point in relation to the other, some associations lost significance. The greater the socioeconomic disadvantage accumulated along life, the lower the levels of TC, LDL and HDL cholesterol (P < 0.05). The socioeconomic gradient of TC and LDL cholesterol was inverse, representing a lower cardiovascular risk for individuals of lower SEP, while the socioeconomic gradient of HDL cholesterol indicated a lower cardiovascular risk for individuals of higher SEP. |
| Databáze: | OpenAIRE |
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