Relation between free triiodothyronine/free thyroxine ratio, echocardiographic parameters and mortality in dilated cardiomyopathy
| Autor: | Dilek Ural, Tayfun Sahin, Baki Komsuoglu, Aysen Agacdiken, Ertan Ural, Ahmet Vural, Guliz Kozdag, Göksel Kahraman |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Cardiomyopathy Dilated Male medicine.medical_specialty Cardiomyopathy Severity of Illness Index Thyroid function tests Internal medicine Humans Medicine Survival rate Aged Ultrasonography Ejection fraction medicine.diagnostic_test business.industry Thyroid Stroke Volume Dilated cardiomyopathy Middle Aged Prognosis medicine.disease Survival Rate Thyroxine medicine.anatomical_structure Case-Control Studies Heart failure Cardiology Triiodothyronine Female Thyroid function Cardiology and Cardiovascular Medicine business Follow-Up Studies |
| Zdroj: | European Journal of Heart Failure. 7:113-118 |
| ISSN: | 1388-9842 |
| DOI: | 10.1016/j.ejheart.2004.04.016 |
| Popis: | Background: Abnormalities in thyroid function are frequent in patients with heart failure and are associated with increased mortality. However, the relation between thyroid hormone levels and echocardiographic parameters has not been investigated sufficiently. Aim: The aims of this study were to investigate the correlations of thyroid hormone levels with echocardiographic parameters and to evaluate their associations with subsequent mortality in a group of patients with dilated cardiomyopathy (DCMP). Methods: Serum levels of thyroid hormones were measured in 111 consecutive patients with DCMP (35 female, 76 male, mean age: 62F12 years). All patients underwent echocardiographic examination and were followed-up for a period of 12F8 months. Results: Twenty-three patients (21%) had abnormalities in thyroid function tests. Free triiodothyronine (fT3)/free thyroxine (fT4) ratio was significantly correlated with most of echocardiographic parameters, such as chamber diameters and ejection fraction. Sixteen patients (14%) died during the follow-up period; their fT3/fT4 ratio was significantly lower than the patients who survived (1.31F0.37 vs. 2.01F0.72, p |
| Databáze: | OpenAIRE |
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