Associations of alveolar bone loss and interleukin-1β levels in one- and two-stage surgical procedures: a randomized prospective trial
| Autor: | Giray Tekin, Ebru Saribas, Tuba Talo Yildirim, Mehmet Çolak, Eylem Ozdemir Kaya, Beran Yokus, Ersin Uysal, Güliz N. Güncü, Filiz Acun Kaya |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male 0301 basic medicine Interleukin-1beta Group ii Alveolar Bone Loss Dentistry Mandible 03 medical and health sciences 0302 clinical medicine Humans Medicine Prospective Studies Stage (cooking) Prospective cohort study General Dentistry Dental alveolus Aged Dental Implants Orthodontics business.industry Gingival Crevicular Fluid 030206 dentistry General Medicine Middle Aged Surgical procedures Interleukin 1β stomatognathic diseases 030104 developmental biology Prospective trial Female Dental Prosthesis Implant-Supported Inflammation Mediators business Loss rate Follow-Up Studies |
| Zdroj: | Acta Odontologica Scandinavica. 75:608-615 |
| ISSN: | 1502-3850 0001-6357 |
| Popis: | Dental implants have been widely and successfully used in recent years as an alternative treatment for removable and fixed dental prostheses. The aim of this randomized prospective study was to determine the alveolar bone loss rate (ABLR) and IL-1β levels in one- and two-stage surgical procedures.This study included 40 patients with a single missing tooth in the posterior mandible; dental implants were inserted using a one-stage surgical procedure (Group I) or a two-stage surgical procedure (Group II). All clinical periodontal parameters were recorded; peri-implant crevicular fluid (PICF) samples were collected before loading (T0) and during the third (T1) and sixth (T2) months after loading. ABLR values were evaluated at T0 and T2 by using dental tomography. PICF was analysed after T2 samples were collected. The study was registered through clinicaltrials.gov; identifier NCT03045458.This study found that, the probing pocket depth was found to be significantly higher in Group I than Group II at both T1 and T2 (p .05). There was no significant difference in other clinical parameters between the groups (p .05). There was a significant difference between Group I ABLR values at T0 and T2 (p .05). The PICF IL-1β levels were not significantly different between groups (p .05).Within the limitations of the short observational period and small sample size of this study, two-stage implant placement shows comparable clinical outcomes to implants placed using a one-stage placement protocol. |
| Databáze: | OpenAIRE |
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