Time to re-evaluate the risks and benefits of valproate and a call for action

Autor: Oliver D. Howes, Thomas R. E. Barnes, Belinda R. Lennox, Sarah Markham, Sridhar Natesan
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Howes, O D, Barnes, T R E, Lennox, B R, Markham, S & Natesan, S 2022, ' Time to re-evaluate the risks and benefits of valproate and a call for action ', British Journal of Psychiatry . https://doi.org/10.1192/bjp.2022.94
Br J Psychiatry
DOI: 10.1192/bjp.2022.94
Popis: SummaryValproate is widely used in psychiatry and neurology, including off-label use. Here we consider its potential benefits and risks, particularly for women of childbearing potential, and the evidence that clinical guidelines are adhered to. Finally, we consider the implications for clinical practice and research into its efficacy in off-label indications.
Databáze: OpenAIRE