Acute Phase Response in Naturally Occurring Coliform Mastitis
| Autor: | Fuminori Nagai, Fumio Hoshi, Keiji Tamura, Katsunori Kudo, Seiichi Kawamura, Atsushi Hatsugaya, Hiromichi Ohtsuka, Kazunori Mori, Masateru Koiwa, Motoshi Tajima |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Physiology Orosomucoid macromolecular substances Body Temperature Leukocyte Count Enterobacteriaceae Internal medicine medicine Animals Acute-Phase Reaction Pulse Coliform mastitis Mastitis Bovine Haptoglobins General Veterinary biology Platelet Count business.industry Haptoglobin Enterobacteriaceae Infections Acute-phase protein food and beverages Interleukin medicine.disease Mastitis Endocrinology Cytokine biology.protein Cytokines Cattle Female Tumor necrosis factor alpha business Acute-Phase Proteins |
| Zdroj: | Journal of Veterinary Medical Science. 63:675-678 |
| ISSN: | 1347-7439 0916-7250 |
| DOI: | 10.1292/jvms.63.675 |
| Popis: | Changes in the activities of serum cytokines and in acute phase response were observed in dairy cows with naturally occurring coliform mastitis. Seven cows with severe mastitis showed systemic and mammary inflammatory response throughout the observation period, and 11 cows with mild mastitis recovered and were able to be milked within 3 days of onset of mastitis. Serum interleukin (IL)-I and tumor necrosis factor (TNF) activities were higher in the severe group than in the mild group at the first appearance of symptoms. Elevated IL-1 activity was evident in the severe group throughout the observation period. Serum alpha-1-acidglycoprotein (alpha1AG) concentration began to rise with the beginning of mastitis in the severe group, and peaked at 9 days. Serum haptoglobin (Hp) concentrations peaked at 3 days, and decreased gradually after 3 days in the severe group. These results showed that there are dynamic changes in serum IL-1 activity and in serum alpha1AG and Hp concentrations in cows with severe coliform mastitis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|