The role of breast tomosynthesis in a predominantly dense breast population at a tertiary breast centre: breast density assessment and diagnostic performance in comparison with MRI
| Autor: | Masako Kataoka, Masakazu Toi, Kaori Togashi, Mami Iima, Akane Ohashi, Shotaro Kanao, Daniel Förnvik |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Adult
medicine.medical_specialty Digital mammography Population Breast Neoplasms Sensitivity and Specificity Digital breast tomosynthesis 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Breast cancer Magnetic resonance imaging Diagnostic techniques and procedures medicine Humans Breast MRI Mammography Radiology Nuclear Medicine and imaging Breast education skin and connective tissue diseases Aged Neuroradiology Aged 80 and over education.field_of_study medicine.diagnostic_test Receiver operating characteristic business.industry General Medicine Middle Aged medicine.disease ROC Curve 030220 oncology & carcinogenesis Breast density Female Radiology business Software |
| Zdroj: | European Radiology |
| ISSN: | 0938-7994 |
| Popis: | To compare breast density measured on digital breast tomosynthesis (DBT) (BI-RADS-based breast composition and fully-automatic estimation) and magnetic resonance imaging (MRI) (BI-RADS amount of fibroglandular tissue), and to evaluate the diagnostic performance in terms of sensitivity and specificity of DBT and MRI in a predominantly dense breast population. Between 2015 and 2016, 152 women with 103 breast malignancies, who underwent 3-T breast MRI and DBT within 2 months’ time, were enrolled in this study. Breast composition/fibroglandular tissue and findings on DBT (two readers) and MRI were reported using BI-RADS 5th edition. Digital mammography images were analysed for breast percent density (PD) using the Libra software tool. A majority of women had dense breasts as categorised by breast composition c (heterogeneously dense) (68%) and d (extremely dense) (15%). The mean PD was 44% (range, 18-89%) and the correlation between breast composition and PD was r = 0.6. The diagnostic performance of MRI was significantly higher compared to DBT for one reader as described by the area under the receiver operating characteristic (ROC) curve (p = 0.004) and of borderline significance for the other reader (p = 0.052). MRI had higher diagnostic performance than DBT in a dense breast population in the tertiary setting. • MRI had higher diagnostic performance than DBT in a dense breast population • Diagnostic performance of DBT was comparable to MRI in women with fatty breasts • MRI was superior to DBT in preoperative breast cancer size assessment |
| Databáze: | OpenAIRE |
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