24-Hour Extracorporeal Membrane Oxygenation in the Hypoxic Dog: Hemodynamics and Pulmonary Gas Exchange

Autor: G. Naud, G. Michalot, J.C. Peyrin, P. Girardet, F. Grimbert, H. Guidicelli
Rok vydání: 1979
Předmět:
Zdroj: European Surgical Research. 11:399-408
ISSN: 1421-9921
0014-312X
DOI: 10.1159/000128090
Popis: Hemodynamic and pulmonary gas exchange values were investigated during 24-hour extracorporeal membrane oxygenation performed on 7 anesthetized dogs subjected to alveolar hypoxia. The chief effects of extracorporeal membrane oxygenation were demonstrated. The duration of the extracorporeal membrane oxygenation was associated with a progressive decline in the systemic arterial pressure and heart rate and a progressive increase in the pulmonary blood flow rate. Left-ventricular stroke work remained constant. The sum of the pulmonary and extracorporeal oxygen uptakes showed no change in spite of large variations in pulmonary flow rate.
Databáze: OpenAIRE