Metatypical basal cell carcinoma: a clinical review
| Autor: | Nicolò Scuderi, Riccardo Frati, Annamaria Corbianco, Mauro Tarallo, Daniele Innocenzi, Umberto Fama, Sergio Delfino, Emanuele Cigna |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Cancer Research Pathology medicine.medical_specialty Skin Neoplasms medicine.medical_treatment Review margins lcsh:RC254-282 lip Young Adult differential-diagnosis Carcinoma medicine Humans Basal cell carcinoma risk-factors Aged Retrospective Studies Aged 80 and over Chemotherapy nonmelanoma skin-cancer management excision epidemiology blacks head business.industry Retrospective cohort study Middle Aged medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Dermatology Radiation therapy medicine.anatomical_structure Oncology Carcinoma Basal Cell Scalp Female Differential diagnosis Skin cancer business |
| Zdroj: | Journal of Experimental & Clinical Cancer Research, Vol 27, Iss 1, p 65 (2008) Journal of Experimental & Clinical Cancer Research : CR |
| ISSN: | 1756-9966 |
| Popis: | Background Metatypical cell carcinoma can be considered as a new entity of skin cancer, being an intermediate typology between basal cell carcinomas and squamous cell carcinomas. The behaviour of the metatypical cell carcinoma lies between these two varieties of skin cancer. It is difficult to perform a differential diagnosis based on morphological and clinical features – therefore it is only possible by accurate histology. Methods The authors have retrospectively analysed clinical records of 240 patients who were affected by metatypical skin cancer and who were treated by surgery, radiotherapy and chemotherapy. Results MTC affected more males than females (62.5% vs 37.5%) than males. The most affected site was the cervicofacial area, 71.7%; then the trunk, 10%; the limbs, 9.6%; the scalp 3.7%; and other regions 5%. A recurrence occurred in 24 cases (10%), mainly in head and neck area. Conclusion In this manuscript, the authors have emphasised the importance of conducting a differential diagnosis, and the importance of the specific treatment for metatypical skin cancer, even though more clinical studies and long-term follow-ups are required before establishing specific guidelines. |
| Databáze: | OpenAIRE |
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