Increased Primary Non-Function in Transplanted Deceased-Donor Kidneys Flushed with Histidine-Tryptophan-Ketoglutarate Solution
| Autor: | R. B. Stevens, A. Murante, Theodore H. Rigley, Jill Y. Skorupa, Govardhana Rao Yannam, E. Holdaway, Lucile E. Wrenshall, M. E. Schriner, Kathleen J. Nielsen, Anna J. Skorupa |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male medicine.medical_specialty Adenosine Allopurinol Urinary system Organ Preservation Solutions Urology Delayed Graft Function Renal function Kidney Function Tests Potassium Chloride Procaine Raffinose Renal Dialysis Cadaver medicine Humans Insulin Immunology and Allergy Mannitol Pharmacology (medical) Kidney transplantation Aged Transplantation Kidney business.industry Panel reactive antibody Middle Aged medicine.disease Glutathione Kidney Transplantation Tissue Donors Surgery Glucose medicine.anatomical_structure Pancreatitis Female business medicine.drug |
| Zdroj: | American Journal of Transplantation. 9:1055-1062 |
| ISSN: | 1600-6135 |
| DOI: | 10.1111/j.1600-6143.2009.02624.x |
| Popis: | Histidine-Tryptophan-Ketoglutarate (HTK) solution is increasingly used to flush and preserve organ donor kidneys, with efficacy claimed equivalent to University of Wisconsin (UW) solution. We observed and reported increased graft pancreatitis in pancreata flushed with HTK solution, which prompted this review of transplanting HTK-flushed kidneys. We analyzed outcomes of deceased-donor kidneys flushed with HTK and UW solutions with a minimum of 12 months follow-up, excluding pediatric and multi-organ recipients. We evaluated patient and graft survival and rejection rates, variables that might constitute hazards to graft survival and renal function. Two-year patient survival, rejection, renal function and graft survival were not different, but early graft loss ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text