Midodrine treatment in children with recurrent vasovagal syncope
| Autor: | Ahmet Vedat Kavurt, Arzu Yılmaz, Fatih Atik, İbrahim Ece, Denizhan Bagrul |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Adolescent
Midodrine 030204 cardiovascular system & hematology 010502 geochemistry & geophysics 01 natural sciences 03 medical and health sciences 0302 clinical medicine Recurrence Syncope Vasovagal Humans Medicine Child Vasovagal syncope Retrospective Studies 0105 earth and related environmental sciences biology business.industry Conventional treatment Syncope (genus) General Medicine medicine.disease biology.organism_classification Treatment dose Anesthesia Pediatrics Perinatology and Child Health Cardiology and Cardiovascular Medicine business medicine.drug |
| Zdroj: | Cardiology in the Young. 31:817-821 |
| ISSN: | 1467-1107 1047-9511 |
| DOI: | 10.1017/s1047951120004746 |
| Popis: | Background:Vasovagal syncope is the most common cause of syncope in childhood and its treatment is not at a satisfactory level yet. We aimed to investigate patients who were diagnosed with vasovagal syncope, did not benefit from conventional treatment, received midodrine treatment, and to evaluate their response to midodrine treatment.Methods:Files of 24 patients who were diagnosed with recurrent vasovagal syncope, did not benefit from non-pharmacological treatments, and received midodrine treatment during June 2017–October 2019 were retrospectively analysed.Results:In total, 24 patients received a treatment dose of midodrine at 5 mg/day (2.5 mg BID) included in the study. The mean number of syncope was 5.75 ± 2.67 prior to treatment. Following treatment, the mean number of syncope was 0.42 ± 0.89. It was observed that syncope episodes did not recur in 17 patients, but it recurred in 4 out of 7 patients in the first 3 months of the treatment and did not recur in the following months. The episodes improved in two patients with an increase in the treatment dose, but the syncope episodes continued in only one patient.Conclusion:It was concluded that midodrine treatment was effective and safe in adolescents with recurrent vasovagal syncope. |
| Databáze: | OpenAIRE |
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