Preliminary results in unresectable head and neck cancer treated by radiofrequency and microwave ablation: Feasibility, efficacy, and safety
| Autor: | Tullio Della Volpe, Carmela Buonomo, Salvatore Cappabianca, G. Belfiore, Francesco Romano, Mariacarmela Sciandra, Maria Paola Belfiore, Guido De Lucia, Tommaso Tartaglione, Antonio Rotondo |
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| Přispěvatelé: | Belfiore, Mp, Sciandra, M, Romano, F, Tartaglione, T, De Lucia, G, Della Volpe, T, Buonomo, C, Cappabianca, Salvatore, Rotondo, Antonio, Belfiore, G. |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Percutaneous
Radiofrequency ablation medicine.medical_treatment very elderly Pilot Projects radiofrequency treatment law.invention computer assisted tomography law cancer control middle aged patient safety advanced cancer nuclear magnetic resonance imaging Microwaves Settore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIA Aged 80 and over clinical article medicine.diagnostic_test adult Microwave ablation feasibility study Ablation aged Treatment Outcome female priority journal Head and Neck Neoplasms palate perforation Catheter Ablation cancer therapy radiofrequency ablation Cardiology and Cardiovascular Medicine complication Article microwave therapy male medicine Humans follow up Radiology Nuclear Medicine and imaging human survival time business.industry Head and neck cancer treatment response Magnetic resonance imaging medicine.disease Radiation therapy clinical effectivene quality of life inoperable cancer Feasibility Studies head and neck cancer skin fistula Neoplasm Recurrence Local Nuclear medicine business Complication |
| Popis: | Purpose To retrospectively determine whether the application of thermal ablation to recurrent and advanced head and neck cancer (HNC) could allow for local tumor control. Materials and Methods From 2002 to 2014, 22 patients (17 men and 5 women; mean age, 64 y; age range, 42–88 y) with unresectable HNC lesions treated with thermal ablation were evaluated. Patients were followed at 3 and 6 months after treatment, every 6 months for 5 years, and yearly thereafter with computed tomography and/or magnetic resonance imaging. The mean follow-up period was 32.2 months (range, 3–51 mo). Results Three of 22 patients with primary lesions are still alive; two of these patients were treated with radiofrequency (RF) ablation and one was treated with microwave (MW) ablation. Of the 19 remaining patients, four were treated with MW ablation and 15 were treated with RF ablation. Imaging revealed partial response in eight patients, and complete response was observed in the remaining 14. There were two major complications after ablation treatment. The mean survival time was 32.9 months ± 3.205 (standard error; 95% confidence interval [CI], 26.6–39.2 mo). The survival time for MW ablation cases (36 mo ± 5.185; 95% CI, 25.8–46.16 mo) was longer than for RF ablation (32.2 mo ± 3.911; 95% CI, 24.5–39.8 mo), although the CI overlap between the groups is large. Conclusions Percutaneous thermal ablation is a promising alternative treatment for local control of incurable HNC. |
| Databáze: | OpenAIRE |
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