Plasmapheresis for Prevention of Recurrent Focal Segmental Glomerulosclerosis of Kidney Allograft in Adult Recipients
| Autor: | Kazunari Tanabe, Takashi Yagisawa, Tatsuro Kawai, K. Ito, Agishi T, Kota Takahashi, S. Fuchinoue, Kazuo Ota, Yasuhiro Iguchi, Hiroshi Kawaguchi, Hiroshi Toma |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Kidney Glomerulus Mild proteinuria Renal function Postoperative Complications Focal segmental glomerulosclerosis Secondary Prevention Humans Transplantation Homologous Medicine Kidney Proteinuria Glomerulosclerosis Focal Segmental business.industry Plasmapheresis General Medicine medicine.disease Kidney Transplantation Surgery Transplantation surgical procedures operative medicine.anatomical_structure Female medicine.symptom business Nephrotic syndrome |
| Zdroj: | Therapeutic Apheresis. 1:191-194 |
| ISSN: | 1091-6660 |
| DOI: | 10.1111/j.1744-9987.1997.tb00040.x |
| Popis: | Nephrotic syndrome due to focal segmental glomerulosclerosis (FGS) frequently recurs even after renal transplantation and may cause renal allograft failure. From January 1983 though April 1995, 11 adult recipients with primary FGS received 11 kidney transplants at our institution, and 3 of them were treated with pretransplant plasma exchange (PE). Other patients did not receive any preoperative PE, and 4 patients lost their grafts due to recurrent FGS (50%). PE was completed 3 times before the transplantation to prevent posttransplant recurrence of FGS. Two recipients did not have any proteinuria or graft dysfunction without posttransplant PE. One patient had mild proteinuria immediately after transplantation, and histological examination showed recurrent FGS. The patient has been undergoing PE once a month (2 years posttransplant). Her renal function is excellent (sCr 1.2 mg/dl), and her FGS is being well controlled by PE. PE seems to be effective for the prevention of the recurrence of FGS following renal transplantation.— |
| Databáze: | OpenAIRE |
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