Popis: |
The radioprotective effect ex vivo, in vitro and in vivo of vitamins was reviewed using PubMed and Embase and conducted according to the PRISMA statement. A total of 38 articles were included in this review, which includes the radioprotective effect of vitamins from ex vivo, in vitro and in vivo studies. Vitamins A, C, D and E were used alone, in combination or with other nutritional and non-nutritional compounds. The use of vitamins in natural form or supplementation can be useful to reduce the radiation effect in the body, organs and/or cells. Only four (A, C, D and E) out of thirteen vitamins have been detected with radioprotective properties being mainly vitamin E followed by vitamin C, A and D. This research was funded by The Spanish Nuclear Safety Council (2696/SRO). I.L. was supported by a Fellowship of the ‘University Junior International Entrepreneurs’ program (UJIE 2019) of University of Valencia and Generalitat Valenciana. N.S.O. was supported by the Universidad de Alicante, Ministerio de Universidades and the European Union “NextGeneration EU/PRTR” through 2022–2024 Margarita Salas grant (MARSALAS22-23). |