Bilateral infiltrative disease of the extraocular muscles: a rare clinical presentation of early stage chronic lymphocytic leukemia

Autor:	M J Potts, Richard W J Lee, Rizwan Malik, Yashin D. Ramkissoon, James Hsuan
Rok vydání:	2008
Předmět:	Male Pathology medicine.medical_specialty genetic structures Chronic lymphocytic leukemia Extraocular muscles Methylprednisolone Functional Laterality Immunophenotyping Lymphocytic Infiltrate Antigens CD Leukemic Infiltration hemic and lymphatic diseases medicine Humans Glucocorticoids Aged Radiotherapy business.industry medicine.disease Combined Modality Therapy Leukemia Lymphocytic Chronic B-Cell Magnetic Resonance Imaging eye diseases Ophthalmology Leukemia medicine.anatomical_structure Oculomotor Muscles Orbital Neoplasms sense organs Bone marrow business Infiltration (medical)
Zdroj:	Orbit (Amsterdam, Netherlands). 27(4)
ISSN:	1744-5108
Popis:	Orbital involvement in chronic lymphocytic leukemia (CLL) is highly unusual and most commonly involves hemorrhage or soft tissue infiltration in advanced disease. We report a case of rapid onset bilateral orbital muscle infiltration as the presenting feature of early stage CLL. In addition, we demonstrate clinico-pathological correlation with an identical chronic B-cell lymphocytic infiltrate in both orbit and bone marrow, with good response of the orbital disease to local radiotherapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b34d09a8712a112ff1fb4d0f230abd https://pubmed.ncbi.nlm.nih.gov/18716967 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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