In VivoDetermination of Body Composition in Zebrafish (Danio rerio) by Quantitative Magnetic Resonance
| Autor: | Lauren A. Fowler, Daniel L. Smith, Robert J. Barry, Lacey N. Dennis, Stephen A. Watts, Mickie L. Powell |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Danio Physiology Adipose tissue 030209 endocrinology & metabolism Bioinformatics Fat mass 03 medical and health sciences 0302 clinical medicine In vivo medicine Animals Zebrafish medicine.diagnostic_test biology Reproducibility of Results Magnetic resonance imaging Original Articles biology.organism_classification Magnetic Resonance Imaging 030104 developmental biology Adipose Tissue Body Composition Animal Science and Zoology Body region Research questions Developmental Biology |
| Zdroj: | Zebrafish. 13:170-176 |
| ISSN: | 1557-8542 1545-8547 |
| DOI: | 10.1089/zeb.2015.1157 |
| Popis: | Zebrafish (Danio rerio) as a model research organism continues to expand its relevance and role in multiple research disciplines, with recent work directed toward models of metabolism, nutrition, and energetics. Multiple technologies exist to assess body composition in animal research models at various levels of detail (tissues/organs, body regions, and whole organism). The development and/or validation of body composition assessment tools can open new areas of research questions for a given organism. Using fish from a comparative nutrition study, quantitative magnetic resonance (QMR) assessment of whole body fat and fat-free mass (FFM) in live fish was performed. QMR measures from two cohorts (n = 26 and n = 27) were compared with chemical carcass analysis (CCA) of FM and FFM. QMR was significantly correlated with chemical carcass values (fat, p |
| Databáze: | OpenAIRE |
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