Laryngeal solitary fibrous tumour
Autor: | Antonio Pastore, Francesco Stomeo, C Bozzo, Davide Padovani |
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Rok vydání: | 2007 |
Předmět: |
Male
Larynx medicine.medical_specialty Mesenchymal tumours benign neoplasm solitary fibrous tumour CD34 CO2 Laser Biopsy Antigens CD34 Fibroma Supraglottic larynx Biomarkers Tumor Humans Medicine Neoplasm Laryngeal Neoplasms Aged Co2 laser Laryngoscopy medicine.diagnostic_test business.industry Solitary fibrous tumour General Medicine medicine.disease Surgery stomatognathic diseases Dyspnea medicine.anatomical_structure Proto-Oncogene Proteins c-bcl-2 Otorhinolaryngology Laser Therapy Supraglottic Neoplasm business Tomography Spiral Computed Follow-Up Studies |
Zdroj: | Auris Nasus Larynx. 34:405-408 |
ISSN: | 0385-8146 |
DOI: | 10.1016/j.anl.2007.01.001 |
Popis: | Solitary fibrous tumours (SFT) are rare neoplasms, with an uncommon laryngeal involvement. Only five cases of laryngeal localization have been described in literature. The following is a case of a 75-year-old man with a supraglottic neoplasm of the larynx; after the biopsy immunohistochemical study demonstrated a strong positivity for vimentin, CD34 and Bcl-2. The neoplasm was consequently classified as a SFT. CO(2) laser surgery of the supraglottic larynx, with a wide excision of the neoplasm, was performed. Twenty-four months on, the patient is alive, well and free of disease. Surgical resection is the treatment of choice for laryngeal SFT, but tumour-free resection margins must be achieved to prevent the possibility of local recurrence. Endoscopic resection by means of the CO(2) laser must be accurately planned with MRI or CT imaging to confirm of this kind of surgery. |
Databáze: | OpenAIRE |
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