Feeding effects on growth during infancy
| Autor: | Kathryn G. Dewey, Zinaida Sevkovskaya, Irina Vanilovich, Michael S. Kramer, Kim F. Michaelsen, Robert W. Platt, Irina Dzikovich, Tong Guo |
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| Předmět: |
Pediatrics
medicine.medical_specialty Cephalometry Breastfeeding Breast milk Cohort Studies Animal science Reference Values medicine Humans Infant Nutritional Physiological Phenomena Milk Human business.industry Body Weight Infant Newborn Water Cereal intake Rural location Body Height Infant Formula Head circumference Breast Feeding Infant formula Fruit Pediatrics Perinatology and Child Health Edible Grain business Breast feeding Cohort study |
| Zdroj: | University of Copenhagen |
| Popis: | Objective To examine the effects of formula, other milks, other liquids, cereals, and other solid foods on growth during infancy. Study design Observational cohort study nested within a large (n=17,046), cluster-randomized trial. We compared growth [weight-for-age, length-for-age, and weight-for-length z scores (WAZ, LAZ, WLZ) and head circumference (HC)] during the intervals 1 to 3, 3 to 6, 6 to 9, and 9 to 12 months, using hierarchical multivariate regression to control for size at the beginning of each interval, maternal education, geographic region, and urban versus rural location. Results Mixed BF and formula/other milk were associated with significantly higher (versus breast milk only) LAZ at 1 to 3 months (+0.038 and +0.047, respectively). In the 3- to 6-month interval, mixed BF and formula/other milk led to significantly higher WAZ (+0.125 and +0.139) and LAZ (+0.081 and +0.075), whereas cereal intake was associated with large and highly significant reductions in both measures (−0.293 and −0.240) and in HC (−0.291 cm). Mixed BF and formula/other milk continued to have positive albeit smaller associations with WAZ and LAZ in the 6- to 9-month and 9- to 12-month intervals. Conclusions Our results confirm the growth-accelerating effects of formula and other milks (versus breast milk) on weight and length gain throughout infancy, with a dose-response gradient and largest associations observed at 3 to 6 months. |
| Databáze: | OpenAIRE |
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