Characterization Of The Interaction Between Phthalocyanine And Amyloid Fibrils By Surface-Enhanced Raman Scattering (Sers)
| Autor: | Viktor Chernii, Mustafa Culha, Sergiy M. Yarmoluk, Nuriye Akbay, Vladyslava B. Kovalska, Ertug Avci, Svitlana Chernii, Mykhaylo Yu. Losytskyy |
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| Rok vydání: | 2018 |
| Předmět: |
010405 organic chemistry
Biochemistry (medical) Clinical Biochemistry 02 engineering and technology macromolecular substances 021001 nanoscience & nanotechnology Amyloid fibril Photochemistry Fibril 01 natural sciences Biochemistry Silver nanoparticle 0104 chemical sciences Analytical Chemistry Characterization (materials science) chemistry.chemical_compound symbols.namesake chemistry Electrochemistry Phthalocyanine symbols Molecule 0210 nano-technology Spectroscopy Raman scattering |
| Popis: | The applicability of surface-enhanced Raman scattering (SERS) on silver nanoparticles for characterization of interaction between the phthalocyanine molecule and amyloid fibril was studied using the axially coordinated Hf phthalocyanine dichloride and fibrils of amyloidogenic protein insulin. The SERS spectra of the phthalocyanine were obtained; the analytical enhancement factor was estimated to be in the range from 4 to 6 × 104. An intensity enhancement in its SERS spectra caused by the presence of fibrillar insulin was observed. Deviation of this enhancement with the change of fibrillar insulin concentration was manifested. |
| Databáze: | OpenAIRE |
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