Heart failure with preserved ejection fraction: strategies for disease management and emerging therapeutic approaches
| Autor: | Peter P. Toth, D F Gauthier |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Heart Failure
medicine.medical_specialty Palliative care Ejection fraction Primary Health Care business.industry Incidence (epidemiology) Clinical course Multimorbidity 030209 endocrinology & metabolism Stroke Volume General Medicine 030204 cardiovascular system & hematology medicine.disease Patient Care Management 03 medical and health sciences 0302 clinical medicine Heart failure medicine Etiology Humans Disease management (health) Intensive care medicine business Heart failure with preserved ejection fraction |
| Zdroj: | Postgraduate medicine. 133(2) |
| ISSN: | 1941-9260 |
| Popis: | Approximately 50% of patients with heart failure (HF) have a preserved ejection fraction (HFpEF), and the incidence of HFpEF is increasing relative to HF with reduced ejection fraction (HFrEF). Both types of HF are associated with reduced survival and increased risk for hospitalization. However, in contrast to HFrEF, there are no approved treatments specifically indicated for HFpEF, and current therapy is largely focused on management of symptoms and comorbidities. Diagnosis of HFpEF in the outpatient setting also presents unique challenges compared with HFrEF because of factors including a high burden of comorbidities in HFpEF and difficulties in distinguishing HFpEF from normal aging. Primary care providers (PCPs) play a pivotal role in the delivery of holistic, patient-centric care from diagnosis to management and palliative care. As the prevalence of HF continues to rise in an aging population, PCPs will need to play a greater role in HFpEF care. This article will review HFpEF etiology and pathophysiology, diagnostic workup, and management of symptoms and comorbidities, with a focus on the critical role of PCPs throughout the clinical course of HFpEF. |
| Databáze: | OpenAIRE |
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