Repeated treatments with rituximab in a patient with amyloid-like IgM deposition neuropathy
Autor: | Masato Kadoya, Jun Shimizu, Kenichi Kaida, Hiroyuki Onoue, Akiko Kadoya, Katsunori Ikewaki |
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Rok vydání: | 2016 |
Předmět: |
medicine.medical_specialty
Weakness Gastroenterology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Atrophy Refractory Internal medicine medicine Clinical/Scientific Notes Amyloid like Immunosuppressive treatment biology business.industry Waldenstrom macroglobulinemia medicine.disease Surgery Neurology Immunoglobulin M biology.protein Rituximab Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery medicine.drug |
Zdroj: | Neurology® Neuroimmunology & Neuroinflammation |
ISSN: | 2332-7812 |
DOI: | 10.1212/nxi.0000000000000220 |
Popis: | Amyloid-like immunoglobulin M (IgM) deposition neuropathy associated with Waldenstrom macroglobulinemia is a rare phenotype of IgM-related neuropathy. The prominent clinical features are painful sensory-dominant neuropathy followed by distal motor weakness and atrophy over a long clinical course1–4 that are refractory to immunosuppressive treatment in many patients.1–6 Herein, we report a case of amyloid-like IgM deposition neuropathy that was successfully treated with rituximab (RTX). |
Databáze: | OpenAIRE |
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