Angio-proliferative lesions in a homosexual boar with features resembling Kaposi's sarcoma
| Autor: | Clarence R. Cole, John H. Hughes, Dilbagh S. Kooner, Gerald M. Penn, Hari M. Sharma, Chandra Prakash, Finnie A. Murray, James R. Blakeslee |
|---|---|
| Rok vydání: | 1983 |
| Předmět: |
Male
endocrine system Pathology medicine.medical_specialty Skin Neoplasms BOAR Swine Immunology Hemangiosarcoma Transplantation Heterologous Mice Nude Biology Thigh Mice Sexual Behavior Animal Dermis Antigen Virology Biopsy Scrotum medicine Animals Kaposi's sarcoma Sarcoma Kaposi Cells Cultured Skin Swine Diseases Mice Inbred BALB C medicine.diagnostic_test Histiocytoma Benign Fibrous urogenital system medicine.disease medicine.anatomical_structure Sarcoma Neoplasm Transplantation |
| Zdroj: | AIDS research. 1(1) |
| ISSN: | 0737-6006 |
| Popis: | Clinical, biopsy and necropsy studies of a homosexual boar revealed angio-proliferative lesions in the skin of the thigh, scrotum and the inguinal lymph node. Angiofibromas were identified in the dermis and subcutis of the thorax and mandible. The avidin-biotin-peroxidase complex technique demonstrated Factor VIII-related antigen as a marker for the neoplastic endothelial cells of the tumors. This boar also showed weight loss and lymphopenia. Explants of tumors were maintained in cultures for 22 passages and cultured cells produced tumors when injected subcutaneously into nude mice. No viral antigen was detected in the cultured tumor cells. Similarities and differences between the lesions in the boar and human Kaposi's sarcoma are discussed. |
| Databáze: | OpenAIRE |
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