Self-Assembly Dipeptide Hydrogel: The Structures and Properties

Autor:	Li Xie, Rongqin Sun, Renlin Zheng, Liangchun Li
Rok vydání:	2021
Předmět:	chemistry.chemical_classification ultrashort peptide Dipeptide Biocompatibility Chemistry biocompatible Peptide Review self-assembly General Chemistry Biocompatible material Combinatorial chemistry chemistry.chemical_compound Self-healing hydrogels Self-assembly hydrogel dipeptide QD1-999
Zdroj:	Frontiers in Chemistry, Vol 9 (2021) Frontiers in Chemistry
ISSN:	2296-2646
DOI:	10.3389/fchem.2021.739791
Popis:	Self-assembly peptide-based hydrogels are well known and popular in biomedical applications due to the fact that they are readily controllable and have biocompatibility properties. A dipeptide is the shortest self-assembling motif of peptides. Due to its small size and simple synthesis method, dipeptide can provide a simple and easy-to-use method to study the mechanism of peptides’ self-assembly. This review describes the design and structures of self-assembly linear dipeptide hydrogels. The strategies for preparing the new generation of linear dipeptide hydrogels can be divided into three categories based on the modification site of dipeptide: 1) COOH-terminal and N-terminal modified dipeptide, 2) C-terminal modified dipeptide, and 3) uncapped dipeptide. With a deeper understanding of the relationship between the structures and properties of dipeptides, we believe that dipeptide hydrogels have great potential application in preparing minimal biocompatible materials.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::767afcfb71cd5b1d7c6ac5f401179dab https://doi.org/10.3389/fchem.2021.739791 Zobrazit plný text záznamu