The influence of extent of neck treatment upon control of cervical lymphadenopathy in cancers of the oral tongue
| Autor: | Robert W. Cantrell, Paul A. Levine, William C. Constable, Leroy J. Korb, Cynthia A. Spaulding |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Cancer Research
medicine.medical_specialty medicine.medical_treatment Cervical lymphadenopathy Tongue medicine Carcinoma Humans Radiology Nuclear Medicine and imaging Tongue Neoplasm Retrospective Studies Radiation business.industry Retrospective cohort study Neck dissection medicine.disease Occult Combined Modality Therapy Surgery Tongue Neoplasms Radiation therapy medicine.anatomical_structure Oncology Head and Neck Neoplasms Carcinoma Squamous Cell medicine.symptom business |
| Zdroj: | International journal of radiation oncology, biology, physics. 21(3) |
| ISSN: | 0360-3016 |
| Popis: | This is a retrospective analysis of the management of the neck in 84 patients with squamous cell carcinoma of the oral tongue treated with curative intent between 1968 and 1985. Patients with a clinically negative neck were treated to the neck only if the patient was thought to have a reasonable probability of occult neck metastases. This policy resulted in a 3-year adjusted neck control rate for N0 patients treated with limited (no, bilateral-partial, or ipsilateral) neck therapy of 38% compared with 95% for patients treated with bilateral, whole neck irradiation (p less than .001). None of the relapses in the patients with limited irradiation were in the treatment portal. Attempted salvage with a neck dissection resulted in cure in only 30%. The 3-year adjusted neck control rate for the N1 and N2 patients treated with total neck irradiation and surgery was 75% and 63%, respectively. The location of recurrence in these patients was in the field of irradiation, but contralateral to the side of the neck dissection. |
| Databáze: | OpenAIRE |
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