A cantilever array-based artificial nose
Autor: | Juergen Fritz, Ch. Gerber, F.M. Battiston, Peter Fornaro, H. J. Güntherodt, Ute Drechsler, Marko Baller, Hugo E. Rothuizen, Peter Vettiger, James K. Gimzewski, Hans Peter Lang, Michel Despont, J.-P. Ramseyer, Ernst Meyer |
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Rok vydání: | 2000 |
Předmět: |
chemistry.chemical_classification
Chemical process Analyte Cantilever Materials science Physics::Instrumentation and Detectors business.industry Surface stress Nanotechnology Polymer Atomic and Molecular Physics and Optics Computer Science::Other Electronic Optical and Magnetic Materials chemistry Principal component analysis Optoelectronics business Instrumentation Layer (electronics) Protein adsorption |
Zdroj: | Ultramicroscopy. 82(1-4) |
ISSN: | 1879-2723 |
Popis: | We present quantitative and qualitative detection of analyte vapors using a microfabricated silicon cantilever array. To observe transduction of physical and chemical processes into nanomechanical motion of the cantilever, swelling of a polymer layer on the cantilever is monitored during exposure to the analyte. This motion is tracked by a beam-deflection technique using a time multiplexing scheme. The response pattern of eight cantilevers is analyzed via principal component analysis (PCA) and artificial neural network (ANN) techniques, which facilitates the application of the device as an artificial chemical nose. Analytes tested comprise chemical solvents, a homologous series of primary alcohols, and natural flavors. First differential measurements of surface stress change due to protein adsorption on a cantilever array are shown using a liquid cell. |
Databáze: | OpenAIRE |
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