Differential diagnosis of solitary pulmonary nodules with dual-source spiral computed tomography
| Autor: | Zhitao Shi, Yanhui Wang, Xueqi He |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty pleural indentation sign vessel convergence sign spicule sign calcification sign 030218 nuclear medicine & medical imaging Lesion 03 medical and health sciences 0302 clinical medicine Immunology and Microbiology (miscellaneous) medicine bronchus sign Bronchus Solitary pulmonary nodule business.industry solitary pulmonary nodule Nodule (medicine) computed tomography enhancement technique General Medicine Articles medicine.disease Spiral computed tomography 3D recombination lobular sign medicine.anatomical_structure 030220 oncology & carcinogenesis Radiology medicine.symptom Differential diagnosis business Sign (mathematics) Calcification |
| Zdroj: | Experimental and Therapeutic Medicine |
| ISSN: | 1792-0981 |
| Popis: | The aim of the present study was to analyze the value of applying dual-source 64-layer spiral computed tomography (CT) in the differential diagnosis of solitary pulmonary nodules (SPNs). Mediastinal windows from 45 cases were selected to study SPNs (maximum diameter, ≤3 cm), and the pathological nature of lesions was determined by clinical and pathological diagnosis. Conventional 64-layer spiral CT scanning, local enhancement and 3D recombination technologies were used to determine the occurrence rate, lesion diameter, degree of enhancement, lobular sign, spicule sign, pleural indentation sign, vessel convergence sign and bronchus sign. The final diagnoses indicated 34 cases of malignant SPNs (75.6%) and 11 benign cases (24.4%). When the nodule diameter in the malignant group was compared with that of the benign group, the difference was not statistically significant (P>0.05). Nodules in the malignant group showed inhomogeneous enhancement while nodules in the benign group showed homogeneous enhancement. The enhanced CT values in the malignant group were higher than those in the benign group, and the difference was statistically significant (P0.05). The sensitivity of CT enhancement was 85.6%, specificity was 79.6%, positive predicated value was 92.3%, and the negative predicted value was 85.2%. In conclusion, SPNs diagnosed by CT enhancement manifested with enhancement degree, lobular sign, calcification, vessel convergence sign and bronchus sign with high diagnostic accuracy. |
| Databáze: | OpenAIRE |
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