Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11)
| Autor: | De Sousa, P.A., Tye, B.J., Bruce, K., Dand, P., Russell, G., Collins, D.M., Greenshields, A., McDonald, K., Bradburn, H., Laurie, A., Canham, M., Kunath, T., Downie, J.M., Bateman, M., Courtney, A. |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Stem Cell Research, Vol 17, Iss 1, Pp 42-48 (2016) De Sousa, P, Tye, B J, Bruce, K, Dand, P, Russell, G, Collins, D M, Greenshields, A, Mcdonald, K, Bradburn, H, Laurie, A, Canham, M, Kunath, T, Downie, J M, Bateman, M & Courtney, A 2016, ' Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11) ', Stem Cell Research . https://doi.org/10.1016/j.scr.2016.04.021 |
| ISSN: | 1876-7753 1873-5061 |
| DOI: | 10.1016/j.scr.2016.04.021 |
| Popis: | The human embryonic stem cell line RCe015-A (RC-11) was derived under quality assured compliance with UK regulation, European Union Directives and International guidance for tissue procurement, processing and storage according to Good Manufacturing Practice (GMP) standards. The cell line was derived from a fragmented cleavage stage embryo voluntarily donated as unsuitable or surplus to fertility requirements following informed consent. RCe015-A (RC-11) shows normal pluripotency marker expression and differentiation to the three germ layers in vitro and in vivo. It has a normal 46XX female karyotype and microsatellite PCR identity, HLA and blood group typing data are available. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|