Nesidioblastosis associated with hyperglycemia in two squirrel monkeys (Saimiri sciureus)
| Autor: | Stephen W. Barthold, C. S. King, Kathleen D. Moody, J. W. Streett |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty endocrine system diseases Nesidioblastosis Enteroendocrine cell Biology Diabetes Complications Lethargy Weight loss Diabetes mellitus Internal medicine Weight Loss Diabetes Mellitus medicine Animals Saimiri General Veterinary Monkey Diseases Pancreatic Diseases Saimiri sciureus Hypothermia medicine.disease medicine.anatomical_structure Endocrinology Hyperglycemia Animal Science and Zoology medicine.symptom Pancreas |
| Zdroj: | Journal of Medical Primatology. 25:361-366 |
| ISSN: | 0047-2565 |
| DOI: | 10.1111/j.1600-0684.1996.tb00029.x |
| Popis: | Nesidioblastosis associated with progressive weight loss and hyperglycemia was diagnosed in two mid-adult, wild-caught, male squirrel monkeys (Saimiri sciureus). Hyperglycemia, glucosuria, and abnormal glucose tolerance test results were found when the monkeys were presented for clinical evaluation for chronic weight loss, episodic dehydration, hypothermia, and lethargy. Immunohistochemical studies of the pancreatic tissue demonstrated that the proliferating endocrine cells stained predominantly glucagon-positive in the most severely affected monkey. |
| Databáze: | OpenAIRE |
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