Mycobacterium bovis infection of total hip arthroplasty after intravesicular Bacillus Calmette-Guérin

Autor: David P. Gwynne-Jones, Brendan Arnold, Ariane Williams
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Arthroplasty Today, Vol 5, Iss 4, Pp 416-420 (2019)
Arthroplasty Today
ISSN: 2352-3441
Popis: Intravesicular application of Bacillus Calmette-Guérin (BCG), a live attenuated strain of Mycobacterium bovis, is effective in the treatment of bladder cancer. However, systemic dissemination and subsequent infection of implants have been reported. We present a case of M. bovis infection of a total hip arthroplasty 5 years after BCG instillation for bladder cancer. He was treated with debridement, antibiotics, irrigation, and prosthesis retention with appropriate antituberculous therapy. At 4 years after surgery and 3 years after cessation of treatment, he has had no recurrence of infection with a good functional outcome. This case highlights the need to consider Mycobacteria infection in patients who have received intravesicular BCG. Debridement and retention of well-fixed implants can be successful in combination with appropriate antituberculous therapy. Keywords: Bacillus Calmette-Guérin, Total hip arthroplasty, Prosthetic joint infection, Mycobacterium bovis, DAIR
Databáze: OpenAIRE