Cylindrical illumination with angular coupling for whole-prostate photoacoustic tomography
| Autor: | Brittani L. Bungart, Ji-Xin Cheng, Tiffany Yang-Tran, Lu Lan, Liang Cheng, Sean Gorsky, Michael O. Koch, Darren Roblyer, Yingchun Cao, Timothy A. Masterson |
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| Rok vydání: | 2019 |
| Předmět: |
0303 health sciences
Materials science Prostate biopsy medicine.diagnostic_test Magnetic resonance imaging medicine.disease 01 natural sciences Article Atomic and Molecular Physics and Optics Imaging phantom 010309 optics Coupling (electronics) 03 medical and health sciences Prostate cancer medicine.anatomical_structure Prostate 0103 physical sciences Photoacoustic tomography Biopsy medicine 030304 developmental biology Biotechnology Biomedical engineering |
| Zdroj: | Biomedical Optics Express. 10:1405 |
| ISSN: | 2156-7085 |
| DOI: | 10.1364/boe.10.001405 |
| Popis: | Current diagnosis of prostate cancer relies on histological analysis of tissue samples acquired by biopsy, which could benefit from real-time identification of suspicious lesions. Photoacoustic tomography has the potential to provide real-time targets for prostate biopsy guidance with chemical selectivity, but light delivered from the rectal cavity has been unable to penetrate to the anterior prostate. To overcome this barrier, a urethral device with cylindrical illumination is developed for whole-prostate imaging, and its performance as a function of angular light coupling is evaluated with a prostate-mimicking phantom. |
| Databáze: | OpenAIRE |
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