Gall bladder mucoceles in Border terriers
| Autor: | Mark Dunning, Faye Swinbourne, Vicki Black, Caroline Kisielewicz, Mickey Tivers, Fergus Allerton, Andrew Kent, Tiago Henriques, Aarti Kathrani, Lucy Barker |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
040301 veterinary sciences extrahepatic biliary tract obstruction Mucocele Disease Standard Article cholecystectomy Gallbladder Diseases urologic and male genital diseases liver Gastroenterology 0403 veterinary science Biliary disease 03 medical and health sciences 0302 clinical medicine Dogs biliary disease Risk Factors Internal medicine medicine Animals Clinical significance Genetic Predisposition to Disease Dog Diseases Retrospective Studies Endocrine disease General Veterinary Hepatology hypercholesterolemia business.industry Case-control study Retrospective cohort study 04 agricultural and veterinary sciences Odds ratio medicine.disease Breed Standard Articles Case-Control Studies 030211 gastroenterology & hepatology SMALL ANIMAL business |
| Zdroj: | Journal of Veterinary Internal Medicine |
| ISSN: | 1939-1676 0891-6640 |
| Popis: | Background Gall bladder mucoceles (GBM) are a leading cause of biliary disease in dogs with several breeds, including the Shetland Sheepdog, American Cocker Spaniel, Chihuahua, Pomeranian, and Miniature Schnauzer apparently predisposed. Objective To determine risk factors, clinical features, and response to treatment of GBM in Border terriers (BT). Animals Medical records of 99 dogs (including 51 BT) with an ultrasonographic (±histopathologic) diagnosis of GBM from three referral centers in the United Kingdom were collected. A control group of 87 similar-aged BT with no ultrasonographic evidence of gall bladder disease was selected for comparison. Method Retrospective case-control study. Odds ratios were calculated to establish breed predisposition. Signalment, presence of endocrine disease, clinicopathologic results, and outcome were compared between the BT, other breeds, and control BTs. Results The odds of identifying a GBM in a BT in this hospital population was 85 times that of all other breeds (95% confidence interval 56.9-126.8). BT had similar clinical signs and clinicopathologic changes to other breeds with GBM. There was no evidence that endocrinopathies were associated with GBM in BT. Clinical significance A robust breed predisposition to GBM is established for the BT. |
| Databáze: | OpenAIRE |
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