Nesfatin–1 As a Novel Appetite-Controlling Peptide: Will Obesity Be History?
| Autor: | Ali Kemal Erenler, Hulusi Atmaca, Ahmet Baydin, Türker Yardan |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
obesity medicine.medical_specialty lcsh:RC648-665 business.industry Endocrinology Diabetes and Metabolism media_common.quotation_subject Peptide Appetite endocrine effects sympathetic activity medicine.disease lcsh:Diseases of the endocrine glands. Clinical endocrinology Obesity Endocrinology chemistry Nesfatin–1 Internal medicine Internal Medicine medicine business media_common |
| Zdroj: | Turkish Journal of Endocrinology and Metabolism, Vol 19, Iss 2, Pp 60-64 (2015) |
| ISSN: | 1301-2193 |
| Popis: | In this study, we aimed to determine the role of a novel peptide – nesfatin 1- in appetite control and define its anorectic mechanism in order to reveal whether it can be used in fight against obesity. We reviewed the articles in the literature investigating the structure, mechanism of effect and experimental usefulness of nesfatin-1. We entered the word “nesfatin” to medical databases and reviewed the literature. Administration of nesfatin-1 maintains a significant reduce in food intake. Its effectiveness in rats is proven. More and more, new researches are in progress to determine its exact mechanism of effect. Nesfatin-1 is a satiety agent. However, use of nesfatin-1 as an anti-obesity agent in humans remains an unclarified field and needs further investigations. Turk Jem 2015; 19: 60-64 |
| Databáze: | OpenAIRE |
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