HLA-DQ2/DQ8 typing for non-biopsy diagnosis of coeliac disease: is it necessary?
| Autor: | Camelia Laura Vaina, Dharamveer Basude, Siba Prosad Paul, Jagrati Chopra, Akshatha Mallikarjuna |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Pediatrics Coeliac disease Secondary care 03 medical and health sciences 0302 clinical medicine Paediatric gastroenterology 030225 pediatrics Internal medicine HLA-DQ Antigens Biopsy Medicine Humans Genetic Predisposition to Disease Societies Medical Retrospective Studies medicine.diagnostic_test business.industry Histocompatibility Testing Triple test HLA-DQ2 Retrospective cohort study Hepatology medicine.disease Celiac Disease Pediatrics Perinatology and Child Health business |
| Zdroj: | Archives of disease in childhood. 104(11) |
| ISSN: | 1468-2044 |
| Popis: | In 2012, the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) revised diagnostic guidance for paediatric coeliac disease (CD).1 It recommended a no-biopsy pathway (NBP) for symptomatic children if so-called ‘triple test’ criteria are satisfied1: The British Society of Paediatric Gastroenterology, Hepatology and Nutrition adopted the guidelines in 2013. ESPGHAN suggested that CD can only be diagnosed by paediatric gastroenterologists or consultant paediatricians with special interest (SPIN) in gastroenterology.1 Many secondary care centres (SCC) in the UK have no SPIN consultant, therefore CD diagnosis is often made by (non-SPIN) general paediatricians. The NBP was implemented in Southwest England (SWE) in May 2013.2 An electronic register is maintained in … |
| Databáze: | OpenAIRE |
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