Dynamics of cerebral edema and the apparent diffusion coefficient of water changes in patients with severe traumatic brain injury. A prospective MRI study

Autor: Dana Darabi, Aram Ter Minassian, Florence Franconi, Laurent Lemaire, Jean-Jacques Le Jeune, Catherine Chapon, Jean-Pierre Benoit, Anne Pasco, Christine Caron
Přispěvatelé: Service de Radiologie, Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM)-Hôpital Larrey [Toulouse], CHU Toulouse [Toulouse]-CHU Toulouse [Toulouse], Ingénierie de la vectorisation particulaire, Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université d'Angers (UA), Service d'anesthésie et réanimation chirurgicale, PRES Université Nantes Angers Le Mans (UNAM)-PRES Université Nantes Angers Le Mans (UNAM), Service Commun d'Analyses Spectroscopiques (SCAS), Service Radiologie et imagerie médicale - Rangueil / Larrey [CHU Toulouse], Pôle imagerie médicale [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Lemaire, Laurent
Rok vydání: 2006
Předmět:
Male
MESH: Brain Edema
Brain Edema
030218 nuclear medicine & medical imaging
Diffusion
Traumatic brain injury
0302 clinical medicine
Edema
Prospective Studies
Neuroradiology
[SDV.MHEP.ME] Life Sciences [q-bio]/Human health and pathology/Emerging diseases
[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases
MESH: Middle Aged
MESH: Kinetics
medicine.diagnostic_test
Brain
General Medicine
Middle Aged
Apparent diffusion coefficient
Female
Radiology
medicine.symptom
Adult
medicine.medical_specialty
Adolescent
Metabolic Clearance Rate
MESH: Diffusion Magnetic Resonance Imaging
Cerebral edema
MESH: Brain
03 medical and health sciences
Magnetic resonance imaging
MESH: Body Water
Body Water
Image Interpretation
Computer-Assisted
medicine
Humans
Effective diffusion coefficient
Radiology
Nuclear Medicine and imaging
Cerebral perfusion pressure
MESH: Adolescent
MESH: Metabolic Clearance Rate
MESH: Humans
business.industry
MESH: Adult
medicine.disease
MESH: Male
MESH: Prospective Studies
Kinetics
Diffusion Magnetic Resonance Imaging
Brain Injuries
MESH: Brain Injuries
business
MESH: Female
MESH: Image Interpretation
Computer-Assisted
030217 neurology & neurosurgery
Diffusion MRI
Zdroj: European Radiology
European Radiology, Springer Verlag, 2006, 16 (7), pp.1501-8. ⟨10.1007/s00330-005-0086-0⟩
European Radiology, 2006, 16 (7), pp.1501-8. ⟨10.1007/s00330-005-0086-0⟩
ISSN: 1432-1084
0938-7994
DOI: 10.1007/s00330-005-0086-0
Popis: The distinction between intracellular (ICE) and extracellular edema (ECE) has a crucial prognostic and therapeutic importance in patients with severe traumatic brain injury (STBI). Indeed, ICE usually leads to cellular death, and maintenance of a cerebral perfusion pressure (CPP) above 70 mmHg is still under debate since this practice may increase ECE. The purpose of this study was to describe the ECE and ICE kinetics associated with STBI using quantitative diffusion MRI. Twelve patients were prospectively studied. The initial ADC in ICE measured on day 1.3+/-0.7 is significantly reduced compared to normal-appearing parenchyma (0.51+/-0.12 * 10(-3) mm2/s vs. 0.76+/-0.03 * 10(-3) mm2/s, n=12, P
Databáze: OpenAIRE
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