Oxytocic activity of blood in parturient and lactating women
| Autor: | J. C. Downes, R. W. Hawker, Walmsley Cf, Blackshaw Jk, Roberts Vs |
|---|---|
| Rok vydání: | 1961 |
| Předmět: |
medicine.medical_specialty
Endocrinology Diabetes and Metabolism Clinical Biochemistry Uterus Oxytocin Biochemistry Uterine contraction Endocrinology Pregnancy Internal medicine Oxytocics medicine Humans Lactation Labor Obstetric business.industry Biochemistry (medical) Plasma kinin medicine.disease Late pregnancy medicine.anatomical_structure Rat uterus Female medicine.symptom business Acetylcholine medicine.drug |
| Zdroj: | The Journal of clinical endocrinology and metabolism. 21 |
| ISSN: | 0021-972X |
| Popis: | The Bristol procedure was used for the extraction of oxytocin from the blood taken from healthy pregnant women during the last trimester of pregnancy and from women during labor. Both oxytocin and oxytocic substance (O.S.) were found in the plasma extracts. The levels of oxytocin in the blood were the same during labor as during late pregnancy, but more O.S. was present in early labor than during pregnancy. The concentration of O.S. was higher in early labor than in late labor. There were no differences in the oxytocic activity (O.A.) of blood samples drawn (a) during and between uterine contractions, and (b) from primiparous and multiparous women. Precautions were taken to exclude the possibility that potassium, 5-hydroxytryptamine, acetylcholine and plasma kinin in the acetone extracts might be acting as interfering substances in the assays. The extracts were assayed on the isolated sensitized rat uterus, by the use of both the superfusion and classic methods. The results obtained suggest that O.S., rat... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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