Botulinum toxin therapy improves masseter spasticity in Amyotrophic Lateral Sclerosis

Autor: Rabab Debs, T. Lenglet, P.-F. Pradat, N. Le Forestier, M. Mongin, Gaëlle Bruneteau, B. Degos, François Salachas, M.Dm. Amador
Přispěvatelé: Département de Recherche en Ethique, Université Paris-Sud - Paris 11 (UP11)
Rok vydání: 2020
Předmět:
Zdroj: Revue Neurologique
Revue Neurologique, Elsevier Masson, 2020, 176, pp.870-873. ⟨10.1016/j.neurol.2020.04.022⟩
ISSN: 0035-3787
DOI: 10.1016/j.neurol.2020.04.022⟩
Popis: Fifteen ALS patients, with troublesome symptoms linked to masseter spasticity, benefited from BoNT-A injections in each masseter. Based on the medical records of patients, the effect of the first injection was assessed one month later. We retrospectively collected information for 12 patients. Eight of them reported a beneficial effect after the injection for the following symptoms: trismus, tongue, lip and cheek biting, and jaw clonus. Five patients indicated that dental care was easier after injection. Our study showed that injections of BoNT-A unequivocally reduced masseter spasticity in ALS patients who subsequently enjoyed greater comfort in their daily living.
Databáze: OpenAIRE