C−C Bond Formation via C−H Bond Activation Using an in Situ-Generated Ruthenium Catalyst

Autor:	Jean-Pierre Genêt, Sylvain Darses, Remi Martinez, Cyrielle Pautigny, Marc‐Olivier Simon, Reynald Chevalier
Rok vydání:	2009
Předmět:	inorganic chemicals Steric effects In situ Ligand chemistry.chemical_element Ruthenium catalyst General Chemistry Bond formation Biochemistry Combinatorial chemistry Catalysis Ruthenium Colloid and Surface Chemistry chemistry otorhinolaryngologic diseases Surface modification
Zdroj:	Journal of the American Chemical Society. 131:7887-7895
ISSN:	1520-5126 0002-7863
Popis:	We report here our full results concerning the possibility of generating in situ from a stable and readily available ruthenium(II) source a highly active ruthenium catalyst for C-H bond activation. The versatility of this catalytic system has been demonstrated, as it offers the possibility of modifying the electronic and steric properties of the catalyst by fine-tuning of the ligands, allowing functionalization of various substrates. Aromatic ketones and imines could be easily functionalized by the reaction with either vinylsilanes or styrenes, depending on the electronic and steric nature of the ligand. Moreover, variable-temperature NMR experiments and the isolation of a ruthenium intermediate complex provided some insights into the generation of the active catalytic ruthenium species in this reaction.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76265fb03d28292af6ce0d008ae0ea58 https://doi.org/10.1021/ja9017489 Zobrazit plný text záznamu