Reliability and validity of the Japanese version of the Dysexecutive Questionnaire (DEX) in Alzheimer's disease: validation of a behavioral rating scale to assess dysexecutive symptoms in Japanese patients with Alzheimer's disease
| Autor: | Yoshihiro Shinagawa, Yoshie Murata, Junko Sato, Shutaro Nakaaki, Hiroshi Tatsumi, Jin Hongo, Tatsuo Akechi, Toshiaki A. Furukawa, Teruo Matsui |
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| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Disease Japan Alzheimer Disease Rating scale Surveys and Questionnaires medicine Humans Apathy Psychiatry Reliability (statistics) Aged Aged 80 and over Psychiatric Status Rating Scales Reproducibility of Results Construct validity Cognition Psychiatry and Mental health Caregivers Research Design Disinhibition Female Geriatrics and Gerontology medicine.symptom Psychology Executive dysfunction |
| Zdroj: | International Journal of Geriatric Psychiatry. 22:951-956 |
| ISSN: | 1099-1166 0885-6230 |
| Popis: | Background Both executive cognitive dysfunction and behavioral problems contribute to dysexecutive symptoms in daily life. The aim of the present study was to develop a behavior rating scale for assessing dysexecutive symptoms in Japanese patients with AD. Method The Dysexecutive Questionnaire (DEX), devised by Burgess et al. (1998), was used to evaluate 122 Japanese patients with AD. The factor structure, internal consistency, test-retest reliability, and construct validity of the Japanese version of the DEX were then examined. Results The Japanese version of the DEX demonstrated a good internal reliability and a good test–retest reliability. Factor analysis revealed three factors that were named ‘apathy’, ‘hyperactivity’ and ‘planning and monitoring process of the purposive action’. The ‘apathy’ factor of the DEX was significantly correlated with the ‘apathy’ score of the Neuropsychiatric Inventory (NPI), while ‘planning and monitoring process’ factor of the DEX was significantly correlated with the total score of the Frontal Assessment Battery (FAB) and the ‘hyperactivity’ factor of the DEX was significantly correlated with the ‘aggression’, ‘euphoria’ and ‘disinhibition’ scores of the NPI. Conclusions The Japanese DEX is a reliable and valid instrument for assessing executive dysfunction conveniently in real life situations of AD patients. While two factors, ‘apathy’ and ‘hyperactivity’, were associated with emotional and behavioral changes, the ‘planning and monitoring process’ was associated with the cognitive executive function in the patients with AD. These findings suggest that both a neuropsychiatric syndrome and cognitive function contribute to the dysexecutive symptoms experienced by AD patients in daily life. Copyright © 2007 John Wiley & Sons, Ltd. |
| Databáze: | OpenAIRE |
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