Transanal (TaTME) vs. laparoscopic total mesorectal excision for mid and low rectal cancer: a propensity score-matched analysis of early and long-term outcomes
Autor: | Dimitri Christoforidis, Sotirios Georgios Popeskou, Martino Munini, Ken Galetti, Raffaello Roesel, Francesco Mongelli |
---|---|
Rok vydání: | 2021 |
Předmět: |
Male
medicine.medical_specialty Colorectal cancer Resection Low rectal cancer Postoperative Complications Internal medicine Long term outcomes Medicine Humans In patient Prospective Studies Propensity Score Aged Transanal Endoscopic Surgery business.industry Rectal Neoplasms Gastroenterology Rectum Hepatology medicine.disease Total mesorectal excision Surgery Treatment Outcome Propensity score matching Laparoscopy Neoplasm Recurrence Local business |
Zdroj: | International journal of colorectal disease. 36(10) |
ISSN: | 1432-1262 |
Popis: | Transanal total mesorectal excision (TaTME) has been proposed as an alternative to laparoscopic total mesorectal excision (LapTME) in distal rectal tumors. Despite encouraging reports, mid- and long-term oncological results are limited. In this study, we aimed at comparing TaTME versus LapTME in patients with mid and low rectal cancer. From January 2012 to December 2019, all patients undergoing either TaTME or LapTME for rectal adenocarcinoma ≤ 12 cm from the anal verge were included. Demographic, clinical, and follow-up data were retrieved from a prospective and audited database, and a propensity score-matched analysis was performed. A total of 144 patients were included, 38 underwent TaTME, and 106 LapTME. The median age was 68.0 (60.2–75.8) years, and 96 (66.7%) patients were male. Median follow-up was 30.6 (20.2–39.8) months in the TaTME group and 49.5 (22.6–68.5) months in the LapTME group. There was one (2.6%) local recurrence in the TaTME group and two (1.9%) in the LapTME group (p = 0.788). There was no difference in the 3-year disease-free survival between groups both in the primary (93% vs. 86%, p = 0.274) and the propensity score-matched analyses (93% vs. 81%, p = 0.132). Conversion to open surgery was less frequent in the TaTME group (none vs. 4 (11.4%), p = 0.041). Intra- and postoperative complications, length of stay, specimen quality, and resection margins were similar between groups. In our experience, TaTME was associated with a less frequent conversion to open surgery but otherwise had similar post-operative results compared to LapTME. Local recurrence and 3-year survival rates were similar. |
Databáze: | OpenAIRE |
Externí odkaz: |