Bilateral lung disease, extensive and diffuse. Diagnosis of pulmonary alveolar proteinosis by bronchoscopic cryobiopsy
| Autor: | Bibiana Vazquez, Sebastián Gando, Roberto Duré, Sebastian Fernandez-Bussy, Gonzalo Labarca, Damián Violi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Pulmonary and Respiratory Medicine
Pathology medicine.medical_specialty Case Report Disease 03 medical and health sciences 0302 clinical medicine Bronchoscopy medicine CryoProbe 030212 general & internal medicine lcsh:RC705-779 Lung medicine.diagnostic_test business.industry lcsh:Diseases of the respiratory system medicine.disease medicine.anatomical_structure 030228 respiratory system Respiratory failure Lung disease Breathing Pulmonary alveolar proteinosis business Rare disease |
| Zdroj: | Respiratory Medicine Case Reports Respiratory Medicine Case Reports, Vol 22, Iss C, Pp 260-262 (2017) |
| ISSN: | 2213-0071 |
| Popis: | Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by the intra-alveolar accumulation of a proteinaceous phospholipid-laden material called surfactant. Clinically, this disease should be suspected with respiratory failure in association with a crazy paving pattern on high-resolution chest computed tomography. We report a 24-year-old gentleman who was referred to us for a history of respiratory failure, treatment with invasive ventilation and tracheostomy. His blood exams and biochemistry were normal. His infectious and rheumatological panel was negative for a secondary disease. A flexible bronchoscopy with a transbronchial biopsy through a CryoProbe was performed. An anatomopathological analysis was periodic acid-Schiff positive for PAP. A CryoProbe is a recently developed diagnostic tool that improves the diagnostic yield in diffuse lung diseases compared to bronchoscopy with transbronchial biopsy. This method should be considered for patients with diffuse lung disease and PAP. |
| Databáze: | OpenAIRE |
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