The Role of Vertebral Porosity and Implant Loading Mode on Bone-Tissue Stress in the Human Vertebral Body Following Lumbar Total Disc Arthroplasty
| Autor: | Noah Bonnheim, Mark F. Adams, Tongge Wu, Tony M. Keaveny |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
Total Disc Replacement Vertebral Body Bending Lumbar vertebrae Bone tissue Bone and Bones Stress (mechanics) Lumbar Humans Medicine Orthopedics and Sports Medicine Intervertebral Disc Orthodontics Lumbar Vertebrae business.industry X-Ray Microtomography Sagittal plane Biomechanical Phenomena medicine.anatomical_structure Female Stress Mechanical Neurology (clinical) Implant Cadaveric spasm business Porosity |
| Zdroj: | Spine. 46:E1022-E1030 |
| ISSN: | 1528-1159 0362-2436 |
| Popis: | STUDY DESIGN Micro-computed tomography- (micro-CT-) based finite element analysis of cadaveric human lumbar vertebrae virtually implanted with total disc arthroplasty (TDA) implants. OBJECTIVE (1) Assess the relationship between vertebral porosity and maximum levels of bone-tissue stress following TDA; (2) determine whether the implant's loading mode (axial compression vs. sagittal bending) alters the relationship between vertebral porosity and bone-tissue stress. SUMMARY OF BACKGROUND DATA Implant subsidence may be related to the bone biomechanics in the underlying vertebral body, which are poorly understood. For example, it remains unclear how the stresses that develop in the supporting bone tissue depend on the implant's loading mode or on typical inter-individual variations in vertebral morphology. METHODS Data from micro-CT scans from 12 human lumbar vertebrae (8 males, 4 females; 51-89 years of age; bone volume fraction [BV/TV] = 0.060-0.145) were used to construct high-resolution finite element models (37 μm element edge length) comprising disc-vertebra-implant motion segments. Implants were loaded to 800 N of force in axial compression, flexion-, and extension-induced impingement. For comparison, the same net loads were applied via an intact disc without an implant. Linear regression was used to assess the relationship between BV/TV, loading mode, and the specimen-specific change in stress caused by implantation. RESULTS The increase in maximum bone-tissue stress caused by implantation depended on loading mode (P |
| Databáze: | OpenAIRE |
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