Endometrial sampling diagnosis of FIGO grade 1 endometrial adenocarcinoma with a background of complex atypical hyperplasia and final hysterectomy pathology
| Autor: | Catherine Rabbitt, Kaled M. Alektiar, Robert A. Soslow, Richard R. Barakat, Mario M. Leitao, Nadeem R. Abu-Rustum, Dennis S. Chi, Siobhan M. Kehoe |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
medicine.medical_specialty Pathology endocrine system diseases medicine.medical_treatment Biopsy Gynecologic oncology Adenocarcinoma urologic and male genital diseases Hysterectomy Atypical hyperplasia Endometrium medicine Humans Aged Gynecology Aged 80 and over Hyperplasia medicine.diagnostic_test business.industry Endometrial cancer Obstetrics and Gynecology Anatomical pathology Middle Aged medicine.disease female genital diseases and pregnancy complications Endometrial Neoplasms Female business Endometrial biopsy |
| Zdroj: | American journal of obstetrics and gynecology. 202(3) |
| ISSN: | 1097-6868 |
| Popis: | Objective The purpose of this study was to determine posthysterectomy pathologic findings in patients with a preoperative endometrial sampling diagnosis of International Federation of Gynecology and Obstetrics (FIGO) grade 1 endometrial adenocarcinoma with a background of complex atypical hyperplasia (CAH). Study Design We reviewed 1423 consecutive cases of endometrial cancer to identify cases with a preoperative endometrial biopsy that demonstrated FIGO grade 1 endometrial adenocarcinoma. Final uterine pathologic findings were grouped into low- and high-risk based on FIGO and Gynecologic Oncology Group criteria. Results We identified 123 cases with a background of CAH and 367 cases without a background of CAH. FIGO grade in the hysterectomy specimen was more than FIGO grade 1 in 11 of 123 cases (8.9%) with a background of CAH, compared with 60 of 359 cases (16.7%) without a background of CAH ( P = .04). Conclusion An endometrial sampling diagnosis of FIGO grade 1 endometrial adenocarcinoma with a background of CAH is more likely to correlate with final posthysterectomy grade than a diagnosis not arising with a background of CAH. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect