Molybdenum disulfide-gold nanoparticle nanocomposite in field-effect transistor back-gate for enhanced C-reactive protein detection
| Autor: | Mohamad Faris Mohamad Fathil, M. K. Md Arshad, N R Dalila, M. N. M. Nuzaihan, Subash C. B. Gopinath |
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| Rok vydání: | 2020 |
| Předmět: |
Materials science
Transistors Electronic Scanning electron microscope Nanochemistry Metal Nanoparticles 02 engineering and technology Biosensing Techniques 010402 general chemistry 01 natural sciences Analytical Chemistry Nanomaterials Nanocomposites chemistry.chemical_compound symbols.namesake Limit of Detection Microscopy Humans Disulfides Molybdenum disulfide Molybdenum business.industry Electric Conductivity Reproducibility of Results Electrochemical Techniques 021001 nanoscience & nanotechnology 0104 chemical sciences C-Reactive Protein chemistry Colloidal gold symbols Optoelectronics Field-effect transistor Gold 0210 nano-technology business Raman spectroscopy Antibodies Immobilized |
| Zdroj: | Mikrochimica acta. 187(11) |
| ISSN: | 1436-5073 |
| Popis: | Nanofabricated gold nanoparticles (Au-NPs) on MoS2 nanosheets (Au-NPs/MoS2) in back-gated field-effect transistor (BG-FET) are presented, which acts as an efficient semiconductor device for detecting a low concentration of C-reactive protein (C-RP). The decorated nanomaterials lead to an enhanced electron conduction layer on a 100-μm-sized transducing channel. The sensing surface was characterized by Raman spectroscopy, ultraviolet–visible spectroscopy (UV-Vis), atomic force microscopy (AFM), scanning electron microscopy (SEM), and high-power microscopy (HPM). The BG-FET device exhibits an excellent limit of detection of 8.38 fg/mL and a sensitivity of 176 nA/g·mL−1. The current study with Au-NPs/MoS2 BG-FET displays a new potential biosensing technology; especially for integration into complementary metal oxide (CMOS) technology for hand-held future device application. |
| Databáze: | OpenAIRE |
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