Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes

Autor: Sundararajan Venkatesan, Malcolm A. Martin, Steven Benn, Paul M. Feorino, Arnold B. Rabson, Daryl Daugherty, Kim E. Boulukos, Thomas M. Folks
Rok vydání: 1985
Předmět:
Zdroj: Science (New York, N.Y.). 229(4720)
ISSN: 0036-8075
Popis: The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified.
Databáze: OpenAIRE