Transcription of novel open reading frames of AIDS retrovirus during infection of lymphocytes
Autor: | Sundararajan Venkatesan, Malcolm A. Martin, Steven Benn, Paul M. Feorino, Arnold B. Rabson, Daryl Daugherty, Kim E. Boulukos, Thomas M. Folks |
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Rok vydání: | 1985 |
Předmět: |
Genetics
Messenger RNA Acquired Immunodeficiency Syndrome Multidisciplinary Genes Viral Transcription Genetic RNA Nucleic Acid Hybridization Biology Provirus biology.organism_classification Virology Deltaretrovirus Virus Open reading frame Retrovirus Viral replication Transcription (biology) DNA Viral Humans RNA Viral Lymphocytes RNA Messenger Repetitive Sequences Nucleic Acid |
Zdroj: | Science (New York, N.Y.). 229(4720) |
ISSN: | 0036-8075 |
Popis: | The retrovirus frequently isolated from patients with the acquired immune deficiency syndrome (AIDS) has two novel open reading frames previously designated "A" and "B." The "A" region was found to be specifically expressed as polyadenylated RNA's of 5.5 and 5.0 kilobases in infected cells. The "B" region was expressed as 1.8- to 2.0-kilobase RNA species. Additional full-length and spliced messenger RNA's of the env region were also identified. |
Databáze: | OpenAIRE |
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