Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC)
| Autor: | Paolo Vineis, Miren Dorronsoro, Athina Arvaniti, Nadia Slimani, Petra H.M. Peeters, Göran Hallmans, Petra H. Lahmann, Naomi E. Allen, Antonia Trichoupoulou, Anja Olsen, Christina Kassapa, Göran Berglund, H. Bas Bueno-de-Mesquita, Sheila Bingham, Sabina Sieri, Carmen Martinez, Rosario Tumino, Carla H. van Gils, Börje Ljungberg, Teresa Norat, Heiner Boeing, Aurelio Barricarte Gurrea, Andrew W. Roddam, Tobias Pischon, Kim Overvad, Domenico Palli, Mazda Jenab, J. Linseisen, J. Ramón Quirós, Elio Riboli, Guillem Pera, Anne Tjønneland, Nikolaus Becker, Elisabet Wirfält, Salvatore Panico, Steffen Weikert, Frederike L. Büchner, Carmen Navarro |
|---|---|
| Přispěvatelé: | Weikert, S, Boeing, H, Pischon, T, Olsen, A, Tjonneland, A, Overvad, K, Becker, N, Linseisen, J, Lahmann, Ph, Arvaniti, A, Kassapa, C, Trichoupoulou, A, Sieri, S, Palli, D, Tumino, R, Vineis, P, Panico, Salvatore, VAN GILS, Ch, Peeters, Ph, BUENO DE MESQUITA, Hb, Buchner, Fl, Ljungberg, B, Hallmans, G, Berglund, G, Wirfalt, E, Pera, G, Dorronsoro, M, Gurrea, Ab, Navarro, C, Martinez, C, Quiros, Jr, Allen, N, Roddam, A, Bingham, S, Jenab, M, Slimani, N, Norat, T, Riboli, E. |
| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Cancer Research medicine.medical_specialty Risk Assessment Sex Factors Interventional oncology [UMCN 1.5] Risk Factors Environmental health Surveys and Questionnaires Vegetables medicine Determinants in Health and Disease [EBP 1] Odds Ratio Humans ddc:610 Prospective Studies Risk factor Sex Distribution Carcinoma Renal Cell Life Style Aged Proportional Hazards Models Proportional hazards model business.industry Incidence (epidemiology) Incidence Odds ratio Feeding Behavior Middle Aged medicine.disease Obesity Kidney Neoplasms Surgery European Prospective Investigation into Cancer and Nutrition Europe Oncology Relative risk Fruit Multivariate Analysis Female business Risk assessment Follow-Up Studies |
| Zdroj: | International Journal of Cancer, 118, 3133-9 International Journal of Cancer, 118, 12, pp. 3133-9 International Journal of Cancer, 118(12), 3133. Wiley-Liss Inc. |
| ISSN: | 0020-7136 |
| Popis: | Contains fulltext : 49915.pdf (Publisher’s version ) (Closed access) We examined the association between fruits and vegetables and risk of renal cell carcinoma (RCC) in the European Prospective Investigation into Cancer and Nutrition (EPIC). Dietary intake data and complete follow-up information on cancer incidence were available for 375,851 participants recruited in EPIC centers of 8 countries. During an average follow-up of 6.2 years, 306 incident cases of RCC were identified. The associations of consumption of total vegetables, total fruits, combined total fruits and vegetables and specific subtypes of vegetables with RCC risk were analyzed using Cox proportional hazards, stratified by centre and adjusted for potential confounders. No significant associations between fruit and vegetable consumption and RCC risk were observed despite a wide range of intake. The estimated relative risks (95% confidence intervals [CI]) in men and women combined were 0.97 (0.85-1.11) per 40 g increase in vegetable intake, 1.03 (0.97-1.08) per 40 g increase in fruit intake and 1.02 (0.93-1.11) per 80 g increase in fruit and vegetable intake combined. Among the vegetable subtypes, an inverse association was observed for root vegetables (RR per 8 g increase: 0.88; 95% CI: 0.78-0.99). These results suggest that total consumption of fruits and vegetables is not related to risk of RCC, although we cannot exclude the possibility that very low consumption is related to higher risk. The relationship of specific fruit and vegetable subgroups with RCC risk warrant further investigation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text