Understanding biochemistry: structure and function of nucleic acids
Autor: | Steve Minchin, Julia Lodge |
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Rok vydání: | 2019 |
Předmět: |
DNA Replication
Translation Cell division Biology 010402 general chemistry 01 natural sciences Biochemistry 03 medical and health sciences chemistry.chemical_compound Transcription (biology) DNA Chromosomes & Chromosomal Structure Review Articles Molecular Biology Gene 030304 developmental biology 0303 health sciences Gene Expression & Regulation Bacteria DNA replication Eukaryota RNA DNA History 20th Century humanities Concept of the gene 0104 chemical sciences Structure and function Nucleic acids Genes chemistry Protein Biosynthesis Nucleic acid Nucleic Acid Conformation Transcription Ribosomes |
Zdroj: | Essays in Biochemistry |
ISSN: | 1744-1358 0071-1365 |
DOI: | 10.1042/ebc20180038 |
Popis: | Nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), carry genetic information which is read in cells to make the RNA and proteins by which living things function. The well-known structure of the DNA double helix allows this information to be copied and passed on to the next generation. In this article we summarise the structure and function of nucleic acids. The article includes a historical perspective and summarises some of the early work which led to our understanding of this important molecule and how it functions; many of these pioneering scientists were awarded Nobel Prizes for their work. We explain the structure of the DNA molecule, how it is packaged into chromosomes and how it is replicated prior to cell division. We look at how the concept of the gene has developed since the term was first coined and how DNA is copied into RNA (transcription) and translated into protein (translation). |
Databáze: | OpenAIRE |
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