Sinulasulfoxide and sinulasulfone, sulfur-containing alkaloids from the Indonesian soft coral Sinularia sp

Autor:	Giorgio Bavestrello, Orazio Taglialatela-Scafati, Carlo Cerrano, Masteria Yunovilsa Putra, Ernesto Fattorusso, Elisabetta Panza, Angela Ianaro
Přispěvatelé:	Putra, M. Y., Ianaro, Angela, Panza, Elisabetta, Bavestrello, G, Cerrano, C, Fattorusso, Ernesto, TAGLIALATELA SCAFATI, Orazio
Rok vydání:	2012
Předmět:	biology Phytanic acid Stereochemistry Coral Organic Chemistry biology.organism_classification Sulfur containing Biochemistry Nmr data chemistry.chemical_compound chemistry Amide Drug Discovery Moiety Sinularia No release
Zdroj:	Tetrahedron Letters. 53:3937-3939
ISSN:	0040-4039
Popis:	Chemical analysis of the Indonesian soft coral Sinularia sp. (order Alcyonacea, family Alcyoniidae) afforded two new alkaloids, named sinulasulfoxide (1) and sinulasulfone (2), characterized by an amide linkage between a phytanic acid moiety and an uncommon sulfur-containing unit. Their complete stereostructures were elucidated by interpretation of MS and NMR data along with CD analysis and chemical modifications. Sinulasulfoxide (1) proved to moderately inhibit LPS-induced NO release.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e8e7c486e09e077947dd4010952bcc https://doi.org/10.1016/j.tetlet.2012.05.095 Zobrazit plný text záznamu Full Text from ScienceDirect