Sinulasulfoxide and sinulasulfone, sulfur-containing alkaloids from the Indonesian soft coral Sinularia sp
Autor: | Giorgio Bavestrello, Orazio Taglialatela-Scafati, Carlo Cerrano, Masteria Yunovilsa Putra, Ernesto Fattorusso, Elisabetta Panza, Angela Ianaro |
---|---|
Přispěvatelé: | Putra, M. Y., Ianaro, Angela, Panza, Elisabetta, Bavestrello, G, Cerrano, C, Fattorusso, Ernesto, TAGLIALATELA SCAFATI, Orazio |
Rok vydání: | 2012 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 53:3937-3939 |
ISSN: | 0040-4039 |
Popis: | Chemical analysis of the Indonesian soft coral Sinularia sp. (order Alcyonacea, family Alcyoniidae) afforded two new alkaloids, named sinulasulfoxide (1) and sinulasulfone (2), characterized by an amide linkage between a phytanic acid moiety and an uncommon sulfur-containing unit. Their complete stereostructures were elucidated by interpretation of MS and NMR data along with CD analysis and chemical modifications. Sinulasulfoxide (1) proved to moderately inhibit LPS-induced NO release. |
Databáze: | OpenAIRE |
Externí odkaz: |