Advancing automation in high-throughput screening: Modular unguarded systems enable adaptable drug discovery

Autor:	Catherine S. Hansel, Darren L. Plant, Geoffrey A. Holdgate, Matthew J. Collier, Helen Plant
Rok vydání:	2021
Předmět:	Pharmacology Automation Drug Discovery Software High-Throughput Screening Assays
Zdroj:	Drug discovery today. 27(8)
ISSN:	1878-5832
Popis:	Challenged by ageing infrastructure and increasingly demanding screening cascades, AstraZeneca High Throughput Screening department has developed advanced automation systems that can support both current needs and future strategies in drug discovery. Through collaboration with HighRes Biosolutions and other third-party vendors, highly versatile automated modular platforms have been designed. Safety features such as collaborative robots allow enhanced system accessibility, and adaptive scheduling software has improved protocol design and system recovery. These innovations have led to significant improvements in system flexibility while maintaining screening productivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75e8c73629c4c76167cbd302ec1cbac3 https://pubmed.ncbi.nlm.nih.gov/35304338 Zobrazit plný text záznamu Full Text from ScienceDirect