Methicillin resistant Staphylococcus aureus ST398 in veal calf farming: Human MRSA carriage related with animal antimicrobial usage and farm hygiene
| Autor: | Graveland, H., Wagenaar, J.A., Heesterbeek, H., Mevius, D.J., van Duijkeren, E., Heederik, D., Advances in Veterinary Medicine, Risk Assessment of Toxic and Immunomodulatory Agents, Strategic Infection Biology, Dep IRAS, Dep Infectieziekten Immunologie, Dep Gezondheidszorg Landbouwhuisdieren |
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| Přispěvatelé: | Advances in Veterinary Medicine, Risk Assessment of Toxic and Immunomodulatory Agents, Strategic Infection Biology, Dep IRAS, Dep Infectieziekten Immunologie, Dep Gezondheidszorg Landbouwhuisdieren |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Veterinary medicine Epidemiology Antibiotics lcsh:Medicine Public Health and Epidemiology/Infectious Diseases medicine.disease_cause Infectious Diseases/Bacterial Infections Hygiene Risk Factors Zoonoses food animals origin Medicine lcsh:Science bacteria Child media_common pet animals Aged 80 and over Public Health and Epidemiology/Occupational and Industrial Medicine Antiinfective agent Multidisciplinary Transmission (medicine) transmission pigs Agriculture Middle Aged Antimicrobial Anti-Bacterial Agents Child Preschool Carrier State Female Research Article ID - Infectieziekten Adult Methicillin-Resistant Staphylococcus aureus Infectious Diseases/Epidemiology and Control of Infectious Diseases Adolescent medicine.drug_class Bioinformatica & Diermodellen media_common.quotation_subject Public Health and Epidemiology/Health Policy strains Young Adult Antibiotic resistance Bio-informatics & Animal models health consequences Animals Humans Epidemiology Bio-informatics & Animal models Aged Epidemiologie Infectious Diseases/Antimicrobials and Drug Resistance business.industry lcsh:R Infant Newborn Infant Methicillin-resistant Staphylococcus aureus agents Carriage Cross-Sectional Studies Epidemiologie Bioinformatica & Diermodellen lcsh:Q Cattle Public Health and Epidemiology/Epidemiology business hospitals |
| Zdroj: | PLoS ONE PLoS One, 5(6). Public Library of Science PLoS ONE, 5 PLoS ONE 5 (2010) PLoS ONE, Vol 5, Iss 6, p e10990 (2010) |
| ISSN: | 1932-6203 |
| Popis: | INTRODUCTION: Recently a specific MRSA sequence type, ST398, emerged in food production animals and farmers. Risk factors for carrying MRSA ST398 in both animals and humans have not been fully evaluated. In this cross-sectional study, we investigated factors associated with MRSA colonization in veal calves and humans working and living on these farms. METHODS: A sample of 102 veal calf farms were randomly selected and visited from March 2007-February 2008. Participating farmers were asked to fill in a questionnaire (n = 390) to identify potential risk factors. A nasal swab was taken from each participant. Furthermore, nasal swabs were taken from calves (n = 2151). Swabs were analysed for MRSA by selective enrichment and suspected colonies were confirmed as MRSA by using slide coagulase test and PCR for presence of the mecA-gene. Spa types were identified and a random selection of each spa type was tested with ST398 specific PCR. The Sequence Type of non ST398 strains was determined. Data were analyzed using logistic regression analysis. RESULTS: Human MRSA carriage was strongly associated with intensity of animal contact and with the number of MRSA positive animals on the farm. Calves were more often carrier when treated with antibiotics, while farm hygiene was associated with a lower prevalence of MRSA. CONCLUSION: This is the first study showing direct associations between animal and human carriage of ST398. The direct associations between animal and human MRSA carriage and the association between MRSA and antimicrobial use in calves implicate prudent use of antibiotics in farm animals. |
| Databáze: | OpenAIRE |
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