Cervical Viral Infections among Asymptomatic Bulgarian Women
| Autor: | Tanja Belovska, Aneta Nacheva, Ayla Murad, Evelina Shikova, Sevinch Kakid, Jeni Staykova |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
0301 basic medicine Adolescent viruses 030106 microbiology Congenital cytomegalovirus infection Cervix Uteri Real-Time Polymerase Chain Reaction medicine.disease_cause Asymptomatic Virus 03 medical and health sciences 0302 clinical medicine Prevalence medicine Humans 030212 general & internal medicine Bulgaria Cervix Genotyping Cervical cancer Transmission (medicine) business.industry Public Health Environmental and Occupational Health General Medicine Middle Aged medicine.disease Virology medicine.anatomical_structure Herpes simplex virus Virus Diseases Female medicine.symptom business Genital Diseases Female |
| Zdroj: | Central European Journal of Public Health. 24:176-179 |
| ISSN: | 1803-1048 1210-7778 |
| Popis: | Aim: Although sexually transmitted viral infections are significant and increasing public health concern, little is known about their prevalence among Bulgarian women. The aim of this study was to investigate cervical viral infections in asymptomatic women. Methods: The study group included 52 randomly selected asymptomatic female volunteers from Bulgarian border town Kardzhali. Cervical specimens were tested by real-time PCR for human papillomaviruses (HPV), herpes simplex virus (HSV) types 1 and 2, cytomegalovirus (CMV), Epstein-Barr virus (EBV), and human immunodeficiency virus (HIV). Results: The investigation demonstrated a high rate (61.5%) of infection with one or more viruses of uterine cervix of participating women considered at low risk. The most prevalent was HPV, found in 32.7% of all women. The genotyping of high-risk (HR) HPV positive specimens showed that HPV16 was the most prevalent HR type. HSV prevalence (30.8%) was almost as high as that of HPV and most women were HSV1 infected. 9.6% and 5.8% of all specimens were positive for EBV and CMV, respectively. Conclusions: Our results indicate that women from Kardzhali region, involved in this study, might be at risk for development of genital tract pathology, including cervical cancer, and for transmission of virus infection sexually and perinatally. |
| Databáze: | OpenAIRE |
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