Cell rearrangement and cell division during the tissue level morphogenesis of evaginating Drosophila imaginal discs
| Autor: | Paul N. Adler, Job Taylor |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Embryo
Nonmammalian Cell division Imaginal disc evagination Cell Green Fluorescent Proteins Morphogenesis Biology Models Biological Article Cell polarity medicine Animals Wings Animal Molecular Biology Process (anatomy) Wing Microscopy Video Metamorphosis Biological Pupa Cell rearrangement Cell Polarity Gene Expression Regulation Developmental Extremities Cell Biology Cell biology Imaginal disc medicine.anatomical_structure Evagination Larva Drosophila Cell Division Cell intercalation Developmental Biology |
| Zdroj: | Developmental biology. 313(2) |
| ISSN: | 1095-564X |
| Popis: | The evagination of Drosophila imaginal discs is a classic system for studying tissue level morphogenesis. Evagination involves a dramatic change in morphology and published data argue that this is mediated by cell shape changes. We have reexamined the evagination of both the leg and wing discs and find that the process involves cell rearrangement and that cell divisions take place during the process. The number of cells across the width of the ptc domain in the wing and the omb domain in the leg decreased as the tissue extended during evagination and we observed cell rearrangement to be common during this period. In addition, almost half of the cells in the region of the leg examined divided between 4 and 8 h after white prepupae formation. Interestingly, these divisions were not typically oriented parallel to the axis of elongation. Our observations show that disc evagination involves multiple cellular behaviors, as is the case for many other morphogenetic processes. |
| Databáze: | OpenAIRE |
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